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Deceleration of single-stranded DNA passing through a nanopore using a nanometre-sized bead structure

DNA sequencing with a solid-state nanopore requires a reduction of the translocation speeds of single-stranded DNA (ssDNA) over 10 μs/base. In this study, we report that a nanometre-sized bead structure constructed around a nanopore can reduce the moving speed of ssDNA to 270 μs/base by adjusting th...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Goto, Yusuke, Haga, Takanobu, Yanagi, Itaru, Yokoi, Takahide, Takeda, Ken-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642329/
https://ncbi.nlm.nih.gov/pubmed/26559466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16640
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