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Dephosphorylation of cdc2 on threonine 161 is required for cdc2 kinase inactivation and normal anaphase.

Exit from metaphase of the cell cycle requires inactivation of MPF, a stoichiometric complex between the cdc2 catalytic and the cyclin B regulatory subunits, as well as that of cyclin A-cdc2 kinase. Inactivation of both complexes depends on proteolytic degradation of the cyclin subunit, yet cyclin p...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EMBO J
Egile Nagusiak: Lorca, T, Labbé, J C, Devault, A, Fesquet, D, Capony, J P, Cavadore, J C, Le Bouffant, F, Dorée, M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 1992
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556712/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1321030/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05302.x
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