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Next-Generation Sequencing in Order to Better Characterize a BRCA Variant of Uncertain Significance
BRCA germline mutations are the most common predisposing factor in familial breast-ovarian cancer syndrome families. However, many screened patients are identified as harboring BRCA variants of uncertain significance (VUS), rather than carrying deleterious germline mutations [Calo et al.: Cancers 20...
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| Publicado no: | Case Rep Oncol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
S. Karger AG
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5566997/ https://ncbi.nlm.nih.gov/pubmed/28868023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000478005 |
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