Positively charged cyclodextrins as effective molecular transporters of active phosphorylated forms of gemcitabine into cancer cells

Positively charged cyclodextrins (PCCDs) are molecular carriers of particular interest for their ability to readily enter into cancer cells. Of main interest, guanidino- and aminoalkyl- PCCDs can be conveniently synthesized and form stable and strong inclusion complexes with various active molecules...

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Publicat a:Sci Rep
Autors principals: Rodriguez-Ruiz, Violeta, Maksimenko, Andrey, Salzano, Giuseppina, Lampropoulou, Maria, Lazarou, Yannis G., Agostoni, Valentina, Couvreur, Patrick, Gref, Ruxandra, Yannakopoulou, Konstantina
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566897/
https://ncbi.nlm.nih.gov/pubmed/28827534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08727-y
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