Positively charged cyclodextrins as effective molecular transporters of active phosphorylated forms of gemcitabine into cancer cells

Positively charged cyclodextrins (PCCDs) are molecular carriers of particular interest for their ability to readily enter into cancer cells. Of main interest, guanidino- and aminoalkyl- PCCDs can be conveniently synthesized and form stable and strong inclusion complexes with various active molecules...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rodriguez-Ruiz, Violeta, Maksimenko, Andrey, Salzano, Giuseppina, Lampropoulou, Maria, Lazarou, Yannis G., Agostoni, Valentina, Couvreur, Patrick, Gref, Ruxandra, Yannakopoulou, Konstantina
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566897/
https://ncbi.nlm.nih.gov/pubmed/28827534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08727-y
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