Cloning by functional complementation of a mouse cDNA encoding a homologue of CDC25, a Saccharomyces cerevisiae RAS activator.

In the yeast Saccharomyces cerevisiae genetic and biochemical evidence indicates that the product of the CDC25 gene activates the RAS/adenylyl cyclase/protein kinase A pathway by acting as a guanine nucleotide protein. Here we report the isolation of a mouse brain cDNA homologous to CDC25. The mouse...

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Detalles Bibliográficos
Publicado en:EMBO J
Main Authors: Martegani, E, Vanoni, M, Zippel, R, Coccetti, P, Brambilla, R, Ferrari, C, Sturani, E, Alberghina, L
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1992
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556682/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1376246/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05274.x
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