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P2X7 Receptor Activation Modulates Autophagy in SOD1-G93A Mouse Microglia
Autophagy and inflammation play determinant roles in the pathogenesis of Amyotrophic Lateral Sclerosis (ALS), an adult-onset neurodegenerative disease characterized by deterioration and final loss of upper and lower motor neurons (MN) priming microglia to sustain neuroinflammation and a vicious cycl...
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| Publicado no: | Front Cell Neurosci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5566572/ https://ncbi.nlm.nih.gov/pubmed/28871219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00249 |
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