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P2X7 Receptor Activation Modulates Autophagy in SOD1-G93A Mouse Microglia

Autophagy and inflammation play determinant roles in the pathogenesis of Amyotrophic Lateral Sclerosis (ALS), an adult-onset neurodegenerative disease characterized by deterioration and final loss of upper and lower motor neurons (MN) priming microglia to sustain neuroinflammation and a vicious cycl...

詳細記述

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書誌詳細
出版年:Front Cell Neurosci
主要な著者: Fabbrizio, Paola, Amadio, Susanna, Apolloni, Savina, Volonté, Cinzia
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566572/
https://ncbi.nlm.nih.gov/pubmed/28871219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00249
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