Phosphorylation of p62 by AMP-activated protein kinase mediates autophagic cell death in adult hippocampal neural stem cells

In the adult brain, programmed death of neural stem cells is considered to be critical for tissue homeostasis and cognitive function and is dysregulated in neurodegeneration. Previously, we have reported that adult rat hippocampal neural (HCN) stem cells undergo autophagic cell death (ACD) following...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Ha, Shinwon, Jeong, Seol-Hwa, Yi, Kyungrim, Chung, Kyung Min, Hong, Caroline Jeeyeon, Kim, Seong Who, Kim, Eun-Kyoung, Yu, Seong-Woon
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2017
Fag:
Protein Synthesis and Degradation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566532/
https://ncbi.nlm.nih.gov/pubmed/28655770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.780874
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