Coagulation factor VIIa-mediated protease-activated receptor 2 activation leads to β-catenin accumulation via the AKT/GSK3β pathway and contributes to breast cancer progression

Cell migration and invasion are very characteristic features of cancer cells that promote metastasis, which is one of the most common causes of mortality among cancer patients. Emerging evidence has shown that coagulation factors can directly mediate cancer-associated complications either by enhanci...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Roy, Abhishek, Ansari, Shabbir A., Das, Kaushik, Prasad, Ramesh, Bhattacharya, Anindita, Mallik, Suman, Mukherjee, Ashis, Sen, Prosenjit
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2017
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566524/
https://ncbi.nlm.nih.gov/pubmed/28522609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.764670
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