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Coagulation factor VIIa-mediated protease-activated receptor 2 activation leads to β-catenin accumulation via the AKT/GSK3β pathway and contributes to breast cancer progression

Cell migration and invasion are very characteristic features of cancer cells that promote metastasis, which is one of the most common causes of mortality among cancer patients. Emerging evidence has shown that coagulation factors can directly mediate cancer-associated complications either by enhanci...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Roy, Abhishek, Ansari, Shabbir A., Das, Kaushik, Prasad, Ramesh, Bhattacharya, Anindita, Mallik, Suman, Mukherjee, Ashis, Sen, Prosenjit
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566524/
https://ncbi.nlm.nih.gov/pubmed/28522609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.764670
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