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Accumulation of autophagosomes confers cytotoxicity

Autophagy comprises the processes of autophagosome synthesis and lysosomal degradation. In certain stress conditions, increased autophagosome synthesis may be associated with decreased lysosomal activity, which may result in reduced processing of the excessive autophagosomes by the rate-limiting lys...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Button, Robert W., Roberts, Sheridan L., Willis, Thea L., Hanemann, C. Oliver, Luo, Shouqing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566519/
https://ncbi.nlm.nih.gov/pubmed/28673965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.782276
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