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Myc inhibition impairs autophagosome formation

Autophagy, a major clearance route for many long-lived proteins and organelles, has long been implicated in cancer development. Myc is a proto-oncogene often found to be deregulated in many cancers, and thus is an attractive target for design of cancer therapy. Therefore, understanding the relations...

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Autores principales: Toh, Pearl P. C., Luo, Shouqing, Menzies, Fiona M., Raskó, Tamás, Wanker, Erich E., Rubinsztein, David C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842180/
https://ncbi.nlm.nih.gov/pubmed/23933736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt381
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