Post-transcriptional regulation of ERBB2 by miR26a/b and HuR confers resistance to tamoxifen in estrogen receptor-positive breast cancer cells

Tamoxifen-resistant (TAMR) estrogen receptor-positive (ER+) breast cancer is characterized by elevated Erb-B2 receptor tyrosine kinase 2 (ERBB2) expression. However, the underlying mechanisms responsible for the increased ERBB2 expression in the TAMR cells remain poorly understood. Herein, we report...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Tan, Sheng, Ding, Keshuo, Chong, Qing-Yun, Zhao, Junsong, Liu, Yuan, Shao, Yunying, Zhang, Yuanyuan, Yu, Qing, Xiong, Zirui, Zhang, Weijie, Zhang, Min, Li, Gaopeng, Li, Xiaoni, Kong, Xiangjun, Ahmad, Akhlaq, Wu, Zhengsheng, Wu, Qiang, Zhao, Xiaodong, Lobie, Peter E., Zhu, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566515/
https://ncbi.nlm.nih.gov/pubmed/28637868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.780973
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