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Glaucoma is associated with plasmin proteolytic activation mediated through oxidative inactivation of neuroserpin

Neuroserpin is a serine protease inhibitor that regulates the activity of plasmin and its activators in the neuronal tissues. This study provides novel evidence of regulatory effect of the neuroserpin on plasmin proteolytic activity in the retina in glaucoma. Human retinal and vitreous tissues from...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gupta, Vivek, Mirzaei, Mehdi, Gupta, Veer Bala, Chitranshi, Nitin, Dheer, Yogita, Vander Wall, Roshana, Abbasi, Mojdeh, You, Yuyi, Chung, Roger, Graham, Stuart
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566433/
https://ncbi.nlm.nih.gov/pubmed/28827627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08688-2
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