Glaucoma is associated with plasmin proteolytic activation mediated through oxidative inactivation of neuroserpin

Neuroserpin is a serine protease inhibitor that regulates the activity of plasmin and its activators in the neuronal tissues. This study provides novel evidence of regulatory effect of the neuroserpin on plasmin proteolytic activity in the retina in glaucoma. Human retinal and vitreous tissues from...

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Publicat a:Sci Rep
Autors principals: Gupta, Vivek, Mirzaei, Mehdi, Gupta, Veer Bala, Chitranshi, Nitin, Dheer, Yogita, Vander Wall, Roshana, Abbasi, Mojdeh, You, Yuyi, Chung, Roger, Graham, Stuart
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566433/
https://ncbi.nlm.nih.gov/pubmed/28827627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08688-2
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