The Histone Methyltransferase MLL1 Directs Macrophage-Mediated Inflammation in Wound Healing and Is Altered in a Murine Model of Obesity and Type 2 Diabetes

Macrophages are critical for the initiation and resolution of the inflammatory phase of wound repair. In diabetes, macrophages display a prolonged inflammatory phenotype in late wound healing. Mixed-lineage leukemia-1 (MLL1) has been shown to direct gene expression by regulating nuclear factor-κB (N...

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發表在:Diabetes
Main Authors: Kimball, Andrew S., Joshi, Amrita, Carson, William F., Boniakowski, Anna E., Schaller, Matthew, Allen, Ronald, Bermick, Jennifer, Davis, Frank M., Henke, Peter K., Burant, Charles F., Kunkel, Steve L., Gallagher, Katherine A.
格式: Artigo
語言:Inglês
出版: American Diabetes Association 2017
主題:
Immunology and Transplantation
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566299/
https://ncbi.nlm.nih.gov/pubmed/28663191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db17-0194
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