The Histone Methyltransferase MLL1 Directs Macrophage-Mediated Inflammation in Wound Healing and Is Altered in a Murine Model of Obesity and Type 2 Diabetes

Macrophages are critical for the initiation and resolution of the inflammatory phase of wound repair. In diabetes, macrophages display a prolonged inflammatory phenotype in late wound healing. Mixed-lineage leukemia-1 (MLL1) has been shown to direct gene expression by regulating nuclear factor-κB (N...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Kimball, Andrew S., Joshi, Amrita, Carson, William F., Boniakowski, Anna E., Schaller, Matthew, Allen, Ronald, Bermick, Jennifer, Davis, Frank M., Henke, Peter K., Burant, Charles F., Kunkel, Steve L., Gallagher, Katherine A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2017
Assuntos:
Immunology and Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566299/
https://ncbi.nlm.nih.gov/pubmed/28663191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db17-0194
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