The Histone Methyltransferase MLL1 Directs Macrophage-Mediated Inflammation in Wound Healing and Is Altered in a Murine Model of Obesity and Type 2 Diabetes

Macrophages are critical for the initiation and resolution of the inflammatory phase of wound repair. In diabetes, macrophages display a prolonged inflammatory phenotype in late wound healing. Mixed-lineage leukemia-1 (MLL1) has been shown to direct gene expression by regulating nuclear factor-κB (N...

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Опубликовано в: :Diabetes
Главные авторы: Kimball, Andrew S., Joshi, Amrita, Carson, William F., Boniakowski, Anna E., Schaller, Matthew, Allen, Ronald, Bermick, Jennifer, Davis, Frank M., Henke, Peter K., Burant, Charles F., Kunkel, Steve L., Gallagher, Katherine A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Diabetes Association 2017
Предметы:
Immunology and Transplantation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566299/
https://ncbi.nlm.nih.gov/pubmed/28663191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db17-0194
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