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Effect of 4-Aminopyridine on Genioglossus Muscle Activity during Sleep in Healthy Adults

Rationale: The reduction in upper airway muscle activity from wakefulness to sleep plays a key role in the development of obstructive sleep apnea. Potassium (K(+)) channels have been recently identified as the downstream mechanisms through which hypoglossal motoneuron membrane excitability is reduce...

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Detalhes bibliográficos
Publicado no:Ann Am Thorac Soc
Main Authors: Taranto-Montemurro, Luigi, Sands, Scott A., Azarbarzin, Ali, Marques, Melania, de Melo, Camila M., Edwards, Bradley A., Eckert, Danny J., Messineo, Ludovico, White, David P., Wellman, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566293/
https://ncbi.nlm.nih.gov/pubmed/28387543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201701-006OC
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