The Combination of Atomoxetine and Oxybutynin Greatly Reduces Obstructive Sleep Apnea Severity. A Randomized, Placebo-controlled, Double-Blind Crossover Trial

Rationale: There is currently no effective pharmacological treatment for obstructive sleep apnea (OSA). Recent investigations indicate that drugs with noradrenergic and antimuscarinic effects improve genioglossus muscle activity and upper airway patency during sleep. Objectives: We aimed to determin...

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Detaylı Bibliyografya
Yayımlandı:Am J Respir Crit Care Med
Asıl Yazarlar: Taranto-Montemurro, Luigi, Messineo, Ludovico, Sands, Scott A., Azarbarzin, Ali, Marques, Melania, Edwards, Bradley A., Eckert, Danny J., White, David P., Wellman, Andrew
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Thoracic Society 2019
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519859/
https://ncbi.nlm.nih.gov/pubmed/30395486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201808-1493OC
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