Epigenetically induced ectopic expression of UNCX impairs the proliferation and differentiation of myeloid cells

We here describe a leukemogenic role of the homeobox gene UNCX, activated by epigenetic modifications in acute myeloid leukemia (AML). We found the ectopic activation of UNCX in a leukemia patient harboring a t(7;10)(p22;p14) translocation, in 22 of 61 of additional cases [a total of 23 positive pat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Daniele, Giulia, Simonetti, Giorgia, Fusilli, Caterina, Iacobucci, Ilaria, Lonoce, Angelo, Palazzo, Antonio, Lomiento, Mariana, Mammoli, Fabiana, Marsano, Renè Massimiliano, Marasco, Elena, Mantovani, Vilma, Quentmeier, Hilmar, Drexler, Hans G, Ding, Jie, Palumbo, Orazio, Carella, Massimo, Nadarajah, Niroshan, Perricone, Margherita, Ottaviani, Emanuela, Baldazzi, Carmen, Testoni, Nicoletta, Papayannidis, Cristina, Ferrari, Sergio, Mazza, Tommaso, Martinelli, Giovanni, Storlazzi, Clelia Tiziana
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566027/
https://ncbi.nlm.nih.gov/pubmed/28411256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.163022
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados