Dynamic relocalization of NHERF1 mediates chemotactic migration of ovarian cancer cells toward lysophosphatidic acid stimulation

NHERF1/EBP50 (Na(+)/H(+) exchanger regulating factor 1; Ezrin-binding phosphoprotein of 50 kDa) organizes stable protein complexes beneath the apical membrane of polar epithelial cells. By contrast, in cancer cells without any fixed polarity, NHERF1 often localizes in the cytoplasm. The regulation o...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Oh, Yong-Seok, Heo, Kyun, Kim, Eung-Kyun, Jang, Jin-Hyeok, Bae, Sun Sik, Park, Jong Bae, Kim, Yun Hee, Song, Minseok, Kim, Sang Ryong, Ryu, Sung Ho, Kim, In-Hoo, Suh, Pann-Ghill
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565956/
https://ncbi.nlm.nih.gov/pubmed/28684865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.88
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