Mouse Sphingosine Kinase 1a Is Negatively Regulated through Conventional PKC-Dependent Phosphorylation at S373 Residue

Sphingosine kinase is a lipid kinase that converts sphingosine into sphingosine-1-phosphate, an important signaling molecule with intracellular and extracellular functions. Although diverse extracellular stimuli influence cellular sphingosine kinase activity, the molecular mechanisms underlying its...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Oh, Yong-Seok, Bae, Sun Sik, Park, Jong Bae, Ha, Sang Hoon, Ryu, Sung Ho, Suh, Pann-Ghill
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671553/
https://ncbi.nlm.nih.gov/pubmed/26642194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143695
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