Mouse Sphingosine Kinase 1a Is Negatively Regulated through Conventional PKC-Dependent Phosphorylation at S373 Residue

Sphingosine kinase is a lipid kinase that converts sphingosine into sphingosine-1-phosphate, an important signaling molecule with intracellular and extracellular functions. Although diverse extracellular stimuli influence cellular sphingosine kinase activity, the molecular mechanisms underlying its...

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Vydáno v:PLoS One
Hlavní autoři: Oh, Yong-Seok, Bae, Sun Sik, Park, Jong Bae, Ha, Sang Hoon, Ryu, Sung Ho, Suh, Pann-Ghill
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671553/
https://ncbi.nlm.nih.gov/pubmed/26642194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143695
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