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CTLA4-CD28 chimera gene modification of T cells enhances the therapeutic efficacy of donor lymphocyte infusion for hematological malignancy

Donor lymphocyte infusion (DLI) followed by hematopoietic stem cell transplantation has served as an effective prevention/treatment modality against the relapse of some hematologic tumors, such as chronic myeloid leukemia (CML). However, the therapeutic efficacies of DLI for other types of leukemia,...

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Dades bibliogràfiques
Publicat a:Exp Mol Med
Autors principals: Park, Hyung Bae, Lee, Ji Eun, Oh, Yu Mi, Lee, Sang Jin, Eom, Hyeon-Seok, Choi, Kyungho
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565951/
https://ncbi.nlm.nih.gov/pubmed/28751785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.104
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