CTLA4-CD28 chimera gene modification of T cells enhances the therapeutic efficacy of donor lymphocyte infusion for hematological malignancy

Donor lymphocyte infusion (DLI) followed by hematopoietic stem cell transplantation has served as an effective prevention/treatment modality against the relapse of some hematologic tumors, such as chronic myeloid leukemia (CML). However, the therapeutic efficacies of DLI for other types of leukemia,...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Park, Hyung Bae, Lee, Ji Eun, Oh, Yu Mi, Lee, Sang Jin, Eom, Hyeon-Seok, Choi, Kyungho
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565951/
https://ncbi.nlm.nih.gov/pubmed/28751785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.104
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