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Wnt5a Induces Catabolic Signaling and Matrix Metalloproteinase Production in Human Articular Chondrocytes

OBJECTIVE: Aberrant Wnt signaling may contribute to osteoarthritis (OA) but the Wnt family members involved have not been fully identified. The purpose of this study was to investigate the role of Wnt5a as a potential mediator of cartilage destruction in OA. DESIGN: Immunohistochemistry to detect Wn...

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Publicado en:Osteoarthritis Cartilage
Main Authors: Huang, G., Chubinskaya, S., Liao, W., Loeser, R.F.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565712/
https://ncbi.nlm.nih.gov/pubmed/28587781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2017.05.018
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