Multipotent Basal Stem Cells, Maintained in Localized Proximal Niches, Support Directed Long-Ranging Epithelial Flows in Human Prostates

Sporadic mitochondrial DNA mutations serve as clonal marks providing access to the identity and lineage potential of stem cells within human tissues. By combining quantitative clonal mapping with 3D reconstruction of adult human prostates, we show that multipotent basal stem cells, confined to discr...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Moad, Mohammad, Hannezo, Edouard, Buczacki, Simon J., Wilson, Laura, El-Sherif, Amira, Sims, David, Pickard, Robert, Wright, Nicholas A., Williamson, Stuart C., Turnbull, Doug M., Taylor, Robert W., Greaves, Laura, Robson, Craig N., Simons, Benjamin D., Heer, Rakesh
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565638/
https://ncbi.nlm.nih.gov/pubmed/28813673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.07.061
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