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Intraflagellar transport velocity is governed by the number of active KIF17 and KIF3AB motors and their motility properties under load
Homodimeric KIF17 and heterotrimeric KIF3AB are processive, kinesin-2 family motors that act jointly to carry out anterograde intraflagellar transport (IFT), ferrying cargo along microtubules (MTs) toward the tips of cilia. How IFT trains attain speeds that exceed the unloaded rate of the slower, KI...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5565462/ https://ncbi.nlm.nih.gov/pubmed/28761002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708157114 |
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