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Mouse macrophages show different requirements for phosphatidylserine receptor Tim4 in efferocytosis

Protein S (ProS) and growth arrest-specific 6 (Gas6) bind to phosphatidylserine (PtdSer) and induce efferocytosis upon binding TAM-family receptors (Tyro3, Axl, and Mer). Here, we produced mouse ProS, Gas6, and TAM-receptor extracellular region fused to IgG fragment crystallizable region in HEK293T...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yanagihashi, Yuichi, Segawa, Katsumori, Maeda, Ryota, Nabeshima, Yo-ichi, Nagata, Shigekazu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565444/
https://ncbi.nlm.nih.gov/pubmed/28768810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705365114
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