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Atypical fracture with long-term bisphosphonate therapy is associated with altered cortical composition and reduced fracture resistance
Bisphosphonates are the most widely prescribed pharmacologic treatment for osteoporosis and reduce fracture risk in postmenopausal women by up to 50%. However, in the past decade these drugs have been associated with atypical femoral fractures (AFFs), rare fractures with a transverse, brittle morpho...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5565436/ https://ncbi.nlm.nih.gov/pubmed/28760963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1704460114 |
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