Intrinsic mechanical behavior of femoral cortical bone in young, osteoporotic and bisphosphonate-treated individuals in low- and high energy fracture conditions

Bisphosphonates are a common treatment to reduce osteoporotic fractures. This treatment induces osseous structural and compositional changes accompanied by positive effects on osteoblasts and osteocytes. Here, we test the hypothesis that restored osseous cell behavior, which resembles characteristic...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zimmermann, Elizabeth A., Schaible, Eric, Gludovatz, Bernd, Schmidt, Felix N., Riedel, Christoph, Krause, Matthias, Vettorazzi, Eik, Acevedo, Claire, Hahn, Michael, Püschel, Klaus, Tang, Simon, Amling, Michael, Ritchie, Robert O., Busse, Björn
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754644/
https://ncbi.nlm.nih.gov/pubmed/26879146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21072
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