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Conformational and chemical selection by a trans-acting editing domain
Molecular sieves ensure proper pairing of tRNAs and amino acids during aminoacyl-tRNA biosynthesis, thereby avoiding detrimental effects of mistranslation on cell growth and viability. Mischarging errors are often corrected through the activity of specialized editing domains present in some aminoacy...
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發表在: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
National Academy of Sciences
2017
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5565427/ https://ncbi.nlm.nih.gov/pubmed/28768811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1703925114 |
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