Homologous trans-editing factors with broad tRNA specificity prevent mistranslation caused by serine/threonine misactivation

Aminoacyl-tRNA synthetases (ARSs) establish the rules of the genetic code, whereby each amino acid is attached to a cognate tRNA. Errors in this process lead to mistranslation, which can be toxic to cells. The selective forces exerted by species-specific requirements and environmental conditions pot...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Liu, Ziwei, Vargas-Rodriguez, Oscar, Goto, Yuki, Novoa, Eva Maria, Ribas de Pouplana, Lluís, Suga, Hiroaki, Musier-Forsyth, Karin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2015
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434731/
https://ncbi.nlm.nih.gov/pubmed/25918376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423664112
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