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A subdomain in the transmembrane domain is necessary for p185neu* activation.

The neu proto-oncogene encodes a protein highly homologous to the epidermal growth factor receptor. The neu protein (p185) has a molecular weight of 185,000 Daltons and, like the EGF receptor, possesses tyrosine kinase activity. neu is activated in chemically induced rat neuro/glioblastomas by subst...

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Bibliografische gegevens
Hoofdauteurs: Cao, H, Bangalore, L, Bormann, B J, Stern, D F
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1992
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC556533/
https://ncbi.nlm.nih.gov/pubmed/1347745
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