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IS10 transposase mutations that specifically alter target site recognition.
IS10 inserts preferentially into particular hotspots. We describe here mutations of IS10 transposase, called 'ATS' that confer Altered Target Specificity. These mutations yield a general relaxation in target specificity but do not affect other aspects of transposition. Thus, the preference...
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| Published in: | EMBO J |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
1992
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556507/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1311257/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05107.x |
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