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Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity.

Fos and Jun form a heterodimeric complex that regulates gene transcription by binding to the activator protein-1 (AP-1) DNA sequence motif. Previously, we demonstrated that the DNA-binding activity of Fos and Jun is regulated in vitro by a novel redox (reduction-oxidation) mechanism. Reduction of a...

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Detalhes bibliográficos
Main Authors: Xanthoudakis, S, Curran, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC556497/
https://ncbi.nlm.nih.gov/pubmed/1537340
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