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Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme.

The DNA binding activity of Fos and Jun is regulated in vitro by a post-translational mechanism involving reduction-oxidation. Redox regulation occurs through a conserved cysteine residue located in the DNA binding domain of Fos and Jun. Reduction of this residue by chemical reducing agents or by a...

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Библиографические подробности
Опубликовано в: :EMBO J
Главные авторы: Xanthoudakis, S, Miao, G, Wang, F, Pan, Y C, Curran, T
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 1992
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556867/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1380454/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05411.x
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