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Structural recognition of tubulysin B derivatives by multidrug resistance efflux transporters in human cancer cells
Multidrug resistance (MDR) is a major hindrance to curative chemotherapy of various human malignancies. Hence, novel chemotherapeutics must be evaluated for their recognition by MDR efflux transporters. Herein we explored the cytotoxic activity of synthetic tubulysin B (Tub-B, EC1009) derivatives (T...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5564821/ https://ncbi.nlm.nih.gov/pubmed/28637003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18385 |
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