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Structure and Function of ABCG2-Rich Extracellular Vesicles Mediating Multidrug Resistance
Multidrug resistance (MDR) is a major impediment to curative cancer chemotherapy. The ATP-Binding Cassette transporters ABCG2, ABCB1 and ABCC2 form a unique defense network against multiple structurally and functionally distinct chemotherapeutics, thereby resulting in MDR. Thus, deciphering novel me...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025911/ https://ncbi.nlm.nih.gov/pubmed/21283667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016007 |
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