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Structure and Function of ABCG2-Rich Extracellular Vesicles Mediating Multidrug Resistance

Multidrug resistance (MDR) is a major impediment to curative cancer chemotherapy. The ATP-Binding Cassette transporters ABCG2, ABCB1 and ABCC2 form a unique defense network against multiple structurally and functionally distinct chemotherapeutics, thereby resulting in MDR. Thus, deciphering novel me...

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Main Authors: Goler-Baron, Vicky, Assaraf, Yehuda G.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025911/
https://ncbi.nlm.nih.gov/pubmed/21283667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016007
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