Ubiquitin as a degradation signal.

For many short-lived eukaryotic proteins, conjugation to ubiquitin, yielding a multiubiquitin chain, is an obligatory pre-degradation step. The conjugated ubiquitin moieties function as a 'secondary' signal for degradation, in that their posttranslational coupling to a substrate protein is...

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Bibliografiske detaljer
Main Authors: Johnson, E S, Bartel, B, Seufert, W, Varshavsky, A
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC556480/
https://ncbi.nlm.nih.gov/pubmed/1311250
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