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Degradation signals in the lysine-asparagine sequence space.
The N-degrons, a set of degradation signals recognized by the N-end rule pathway, comprise a protein's destabilizing N-terminal residue and an internal lysine residue. We show that the strength of an N-degron can be markedly increased, without loss of specificity, through the addition of lysine...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171667/ https://ncbi.nlm.nih.gov/pubmed/10545113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.21.6017 |
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