ロード中...
In silico gene expression analysis reveals glycolysis and acetate anaplerosis in IDH1 wild-type glioma and lactate and glutamate anaplerosis in IDH1-mutated glioma
Hotspot mutations in isocitrate dehydrogenase 1 (IDH1) initiate low-grade glioma and secondary glioblastoma and induce a neomorphic activity that converts α-ketoglutarate (α-KG) to the oncometabolite D-2-hydroxyglutarate (D-2-HG). It causes metabolic rewiring that is not fully understood. We investi...
保存先:
| 出版年: | Oncotarget |
|---|---|
| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2017
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5564758/ https://ncbi.nlm.nih.gov/pubmed/28467784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17106 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|