The tumor suppressor interferon regulatory factor 8 inhibits β-catenin signaling in breast cancers, but is frequently silenced by promoter methylation

Interferon (IFN) regulatory factor 8 is encoded by a novel candidate tumor suppressor gene (IRF8), its promotor is frequently methylated in multiple cancers. However, the promoter methylation status, functions and underlying mechanisms of IRF8 in breast cancer remain unclear. We found that IRF8 was...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Luo, Xinrong, Xiong, Xin, Shao, Qing, Xiang, Tingxiu, Li, Lili, Yin, Xuedong, Li, Xia, Tao, Qian, Ren, Guosheng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2017
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564732/
https://ncbi.nlm.nih.gov/pubmed/28388578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16511
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