Aurora kinase B dependent phosphorylation of 53BP1 is required for resolving merotelic kinetochore-microtubule attachment errors during mitosis

Defects in resolving kinetochore-microtubule attachment mistakes during mitosis is linked to chromosome instability associated with carcinogenesis as well as resistance to cancer therapy. Here we report for the first time that tumor suppressor p53-binding protein 1 (53BP1) is phosphorylated at serin...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Wang, Haibo, Peng, Bin, Pandita, Raj K., Engler, David A., Matsunami, Risë K., Xu, Xingzhi, Hegde, Pavana M., Butler, Brian E., Pandita, Tej K., Mitra, Sankar, Xu, Bo, Hegde, Muralidhar L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564716/
https://ncbi.nlm.nih.gov/pubmed/28415769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16225
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