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Improved Risk Stratification in Pediatric Septic Shock Using Both Protein and mRNA Biomarkers. PERSEVERE-XP

Rationale: We previously derived and validated the Pediatric Sepsis Biomarker Risk Model (PERSEVERE) to estimate baseline mortality risk in children with septic shock. The PERSEVERE biomarkers are serum proteins selected from among the proteins directly related to 80 mortality risk assessment genes....

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Pubblicato in:Am J Respir Crit Care Med
Autori principali: Wong, Hector R., Cvijanovich, Natalie Z., Anas, Nick, Allen, Geoffrey L., Thomas, Neal J., Bigham, Michael T., Weiss, Scott L., Fitzgerald, Julie C., Checchia, Paul A., Meyer, Keith, Quasney, Michael, Hall, Mark, Gedeit, Rainer, Freishtat, Robert J., Nowak, Jeffrey, Raj, Shekhar S., Gertz, Shira, Grunwell, Jocelyn R., Lindsell, Christopher J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564676/
https://ncbi.nlm.nih.gov/pubmed/28324661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201701-0066OC
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