Cationic liquid crystalline nanoparticles for the delivery of synthetic RNAi-based therapeutics

RNA interference (RNAi)-based therapeutics have been used to silence the expression of targeted pathological genes. Small interfering RNA (siRNAs) and microRNA (miRNAs) inhibitor have performed this function. However, short half-life, poor cellular uptake, and nonspecific distribution of small RNAs...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Gentile, Emanuela, Oba, Taro, Lin, Jing, Shao, Ruping, Meng, Feng, Cao, Xiaobo, Lin, Heather Y., Mourad, Majidi, Pataer, Apar, Baladandayuthapani, Veerabhadran, Cai, Dong, Roth, Jack A., Ji, Lin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564640/
https://ncbi.nlm.nih.gov/pubmed/28637023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18421
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