HIF-2α promotes the formation of vasculogenic mimicry in pancreatic cancer by regulating the binding of Twist1 to the VE-cadherin promoter

Vasculogenic mimicry (VM) is a blood supply modality that occurs independently of endothelial cell angiogenesis. Hypoxia and the epithelial-mesenchymal transition (EMT) induce VM formation by remodeling the extracellular matrix. Our previous study demonstrated that hypoxia-inducible factor-2 alpha (...

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Vydáno v:Oncotarget
Hlavní autoři: Yang, Jian, Zhu, Dong-Ming, Zhou, Xiao-Gang, Yin, Ni, Zhang, Yi, Zhang, Zi-Xiang, Li, De-Chun, Zhou, Jian
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564606/
https://ncbi.nlm.nih.gov/pubmed/28599281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17999
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