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Alpha-mangostin induces apoptosis through activation of reactive oxygen species and ASK1/p38 signaling pathway in cervical cancer cells

Alpha-mangostin, a natural xanthonoid, has been reported to possess the anti-cancer property in various types of human cancer. However, its effects and mechanism of α-mangostin in cervical cancer remain unclear. We found that α-mangostin effectively inhibited cell viability, resulted in loss of mito...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lee, Chien-Hsing, Ying, Tsung-Ho, Chiou, Hui-Ling, Hsieh, Shu-Ching, Wen, Shiua-Hua, Chou, Ruey-Hwang, Hsieh, Yi-Hsien
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564576/
https://ncbi.nlm.nih.gov/pubmed/28537893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17659
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