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Liposomal co-delivered oleanolic acid attenuates doxorubicin-induced multi-organ toxicity in hepatocellular carcinoma

Doxorubicin in combination with other cytotoxic drugs has clinical advantages. However, doxorubicin-induced cardiotoxicity negatively impacts clinical utility and outcomes. Cardiotoxicity can result from increased oxidative stress or from a local cytochrome P450 mediated increase in 20-hydroxy-5, 8,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Sarfraz, Muhammad, Afzal, Attia, Raza, Shahid Masood, Bashir, Sajid, Madni, Asadullah, Khan, Muhammad Waseem, Ma, Xiang, Xiang, Guangya
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564550/
https://ncbi.nlm.nih.gov/pubmed/28525367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17559
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