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Use of a MCL-1 inhibitor alone to de-bulk melanoma and in combination to kill melanoma initiating cells
MCL-1 (BCL-2 family anti-apoptotic protein) is responsible for melanoma's resistance to therapy. Cancer initiating cells also contribute to resistance and relapse from treatments. Here we examined the effects of the MCL-1 inhibitor SC-2001 in killing non melanoma-initiating-cells (bulk of melan...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5564524/ https://ncbi.nlm.nih.gov/pubmed/27086916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8695 |
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